Designing of peptides with desired half-life in intestine-like environment

BMC Bioinformatics

Table 3 The performance SVM based models developed on HL16 dataset using composition and binary pattern

Input features	Residues in peptides	Total attributes	R	R²	MAE
Amino acid composition	All residues	20	0.91	0.82	0.18
	5 N-terminal		0.57	0.32	0.23
	10 N-terminal		0.77	0.60	0.24
	5 C-terminal		0.37	0.13	0.27
	10 C-terminal		0.81	0.65	0.24
Binary pattern	All residues	320	0.13	0.01	0.18
	5 N-terminal	100	0.17	0.02	0.20
	5 C-terminal	100	0.03	-0.002	0.18
	10 N-terminal	200	0.22	0.02	0.18
	10 C-terminal	200	0.09	-0.002	0.18
Dipeptide composition	All residues	400	0.90	0.39	0.23
Tripeptide composition	All residues	8000	0.90	0.31	0.24

ISSN: 1471-2105