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Figure 2 | BMC Bioinformatics

Figure 2

From: Quality versus accuracy: result of a reanalysis of protein-binding microarrays from the DREAM5 challenge by using BayesPI2 including dinucleotide interdependence

Figure 2

Scatter plots of algorithm performance rank order versus PBM training data quality. A, B, C, and D show scatter plots of algorithm performance rank order of 66 mouse TFs versus the length of the major axis of the PCA ellipse (i.e. 99.73% limit of PCA quality control ellipse), the length of the minor axis of the PCA ellipse, correlation coefficient between signal intensities and background intensities, and regression coefficients, respectively. Both PCA ellipse and regression coefficient are based on MA scatter plots for PBM training datasets. In the figure, the black smooth lines are fitted linear regression lines to the scatter plots, and the P-values of the regression lines are indicated at the top of each figure. The rank order of TFs (i.e. 66 TFs were sorted in decreasing order by mean final algorithm performance scores) is adopted from Figure 2 of the DREAM5 challenge paper.

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