Skip to main content
Figure 4 | BMC Bioinformatics

Figure 4

From: Towards accurate characterization of clonal heterogeneity based on structural variation

Figure 4

A loss-of-heterozygosity deletion in NRXN3 in COLO-829. Plotted is an image from the integrative genome viewer (IGV) that represents read alignment over this deletion (chr14:79175898–79184805) in the tumor sample (top panel) and in the normal sample (bottom panel). The discordant read pairs (dark-red bars connected by long grey lines) and drop in coverage (white space in the center) correspond to the start and the end of the deletion (red horizontal bar). VAFs are estimated by BreakDown to be 1.0 and 0.49, respectively in the tumor and the normal.

Back to article page