Figure 2
From: Critical assessment of coalescent simulators in modeling recombination hotspots in genomic sequences
A simple ancestral recombination graph for illustrative purpose. The ancestral sequence is “ACGT” (top). After four mutations (denoted by m 1 , m 2 , m 3 , and m 4 , respectively) and two recombination events [denoted by (2, 3) and (3, 4), respectively], it has evolved into five (four distinct) present-day sequences, i.e., “TGGT”, “TGGT” (i.e., same as the sequence to the left), “TCCT”, “ACGT”, and “ACGA”. Notation m 1 indicates an A→T mutation on locus 1. Notation (2, 3) denotes a recombination between alleles at loci 2 and 3.