Skip to main content
Figure 9 | BMC Bioinformatics

Figure 9

From: MOSBIE: a tool for comparison and analysis of rule-based biochemical models

Figure 9

Comparison of two models of EGFR signaling from the BioModels database [14]. Left column: BIOMD0000000019 (Model 19) [42]; right column: BIOMD0000000048 (Model 48) [43]. Contact maps with custom layout (top row) and similarity comparison with layout stabilization (bottom row) for the two models are shown. The region highlighted in green shows that the two models share a core set of molecules, components, and interactions. Model 19 is comprised of 87 species and 236 reactions, whereas Model 48 is comprised of 23 species and 47 reactions. Note that both models are encoded in SBML and are not rule-based models. Contact map representations were generated by extracting the implicit molecular structures of these models using the Atomizer [44].

Back to article page