Figure 5
From: Modeling T cell receptor recognition of CD1-lipid and MR1-metabolite complexes
Predictions of GEM TCR complexes with CD1b-Antigen. (A) GEM TCR models bound to CD1b-Ag and Yae62 TCR bound to H-2 Kb-peptide (PDB code 3RGV). Colors are: GEM α chains, blue; GEM β chains, salmon; Yae62 α chain, cyan; Yae62 β chain, yellow; CD1b/MHC, green; antigens MA/GMM/peptide, magenta. (B) Clone 18 GEM TCR modeled interface with CD1b-MA. (C) Clone 42 GEM TCR modeled interface with CD1b-GMM. For (B) and (C), key TCR side chains contacting antigen head group and inter-atomic distances are indicated.