Figure 7

Comparison of conformational variability, average temperature factor and presence of crystal contacts in CDK2. Alignment position is labelled on the X axis. Monomeric chains are coloured blue and protein bound chains, red. (a) conformational variability using curvature and torsion (b) average normalised temperature factor (c) crystal contacts as calculated using CCP4 [41] NCONT. The value plotted is the average proportion of structures with at least one contact within 5 Å. The location of the PSTAIRE helix is highlighted in orange and the T-loop is highlighted in yellow.