Figure 7

Distribution of FPKM CVs per KEGG pathway. A) The kernel density, per pathway, of FPKM CVs for the pathway’s genes found in our data set. The Top graph show pathways detected much more strongly by the RA method than by the PE and MI. The second graph show pathways picked up slightly more strongly by RA. The third graph show pathways detected equally well by all three methods. The bottom graph contains pathways better picked up by PE and MI compared to the RA method. The better the RA method detects a pathway compared to the other two, the further left its curve sits. The dotted purple lines indicate how the distributions shift towards the left as one goes up the graph series. B and C, Two pathways, one from the top graph, and one from the third graph, showing the densities for the subgroup of genes that each method detects at V(G)₅ = 2220. The pathway CV(FPKM) density (gray), RA (red), MI (blue), PE (green).