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Table 3 The running time of the standard estimation procedure and the FastMG procedure with different splitting algorithms and k values for the HSSP data set

From: FastMG: a simple, fast, and accurate maximum likelihood procedure to estimate amino acid replacement rate matrices from large data sets

Matrices

Building trees (hours)

Estimating parameters (hours)

Total time (hours)

HSSP 8 R / HSSP 8 T

10.7/7.4

6.3/3.6

17.0/11.0

HSSP 16 R / HSSP 16 T

22.9/19.0

6.0/3.9

28.9/22.9

HSSP 24 R / HSSP 24 T

32.6/29.9

5.7/3.9

38.3/33.8

HSSP 32 R / HSSP 32 T

42.3/40.0

5.5/3.9

47.8/43.9

HSSP 64 R / HSSP 64 T

73.7/71.7

5.2/4.1

78.9/75.8

HSSPS

319.5

4.2

323.7