Table 1 Open source tools for high-throughput screening

CellProfiler & CP Analyst [17]

Python

Joint Boosting

User friendly

WND-CHARM [18]

C++

Weighted Nearest Neighbor

Many image features

Enhanced CellClassifier [19]

Matlab

SVM

Good classifier

FARSIGHT [20]

C++

Supervised Spectral Clustering

Programmer friendly

CellMorph, EBImage [21]

R

SVM

Link to machine

learning algorithms

CellCognition [22]

Python

Hidden Markov Model

Classifies movies

CellXpress [23]

C++

R package for SVM

Phenotypic profiling

Ilastik [24]

Python

Random Forest

Interactive segmentation

BIOCAT [6]

Java

Nearest Neighbor, Random Forest,

User friendly and extensible

SVM and Decision Trees