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Figure 2 | BMC Bioinformatics

Figure 2

From: Inferring clonal evolution of tumors from single nucleotide somatic mutations

Figure 2

Derivation of partial order plot. (Left column) Posterior distribution over trees, each tree has a 0.5 probability under the posterior. (Right column) Derived partial order plot. Nodes correspond to SNVs. Edge thickness is proportional to the posterior probability that parent SNVs is in a subclonal lineage that is the parent of the one containing the child SNV. SNV nodes are ordered based on a topological sort implemented as the “layered graph drawing method” in Graphviz [24]. In this example, SNV A is always in a subclonal lineage that is the parent of B but the same is true with probability 0.5 for C.

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