Figure 2

Example output showing the heatmaps produced by querying the mRNA sequence of the Homo sapiens Hairless ( HR ) transcript (NM_005144) against Mus musculus Hairless ( Hr ) (NM_021877). The solid bars above the heatmap indicate the ORFs on the transcript. The output lists the most conserved uPEPs first. The heatmap generated by the query sequence is shown first; in this case human HR aligned with mouse Hr transcript. The reciprocal heatmap generated using the reference sequence is shown below (mouse Hr transcript versus human HR). The inclusion of the Reference Alignment is selectable by the user. The unformatted aligned sequence can be viewed using a hyperlink shown above the heatmap.