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Table 2 Total number newly significant/insignificant (p < 0.05) gene sets with DFLAT

From: DFLAT: functional annotation for human development

Study

Newly significant

Newly insignificant

Trisomy 21

47

29

Trisomy 18

37

16

Maternal/fetal blood*

22

6

BPD

50

27

Leukemia

108

49

  1. Total number of gene sets (either “unique” or “common”) showing enrichment (GSEA p < 0.05) with only the DFLAT collection (“Newly significant”) or the GOA collection (“Newly insignificant”).
  2. *Because of the design of this study, these numbers report the significant changes only in the meaningful direction: gene sets that might characterize fetal gene expression in maternal blood. Changes in the other direction likely characterize maternal response to Cesarean delivery.