Figure 4From: LDsplit: screening for cis-regulatory motifs stimulating meiotic recombination hotspots by analysis of DNA sequence polymorphismsComparison of average strengths of hotspots between SNP alleles that preserve and disrupt the PRDM9 motif of CCTCCCT. We collected hotspot-SNP pairs with significant LDsplit p-values where the SNPs are inside PRDM9 motif. For SNP alleles preserving the motif form of CCTCCCT, the allele-specific recombination profiles of the hotspots are averaged into the red profile in the figure. For the same list of hotspot-SNP pairs, the blue profile plots the average recombination hotspots estimated from haplotypes of SNP alleles that disrupt the CCTCCCT motif.Back to article page