Table 1 Parameter settings of the different kinds of scenarios
From: Stability SCAD: a powerful approach to detect interactions in large-scale genomic study
Feature of simulated set | Scenario | Number of nonzero main effects | Number of nonzero interactions | Locations of causal variants | Designed OR |
|---|---|---|---|---|---|
ABCC4 (327 SNPs, 53301 two-way interactions) | A1/A2/A3 | 0 | 1 | SNP33 × SNP197 | 1.5/1.4/1.3 |
B1/B2/B3 | 1 | 1 | SNP18 + SNP18 × SNP134 | 1.5/1.4/1.3 | |
|  | C1/C2/C3 | 2 | 1 | SNP33 + SNP134 + SNP33 × SNP134 | 1.5/1.4/1.3 |