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Figure 2 | BMC Bioinformatics

Figure 2

From: Identification of pathogen genomic variants through an integrated pipeline

Figure 2

CNV detection in a cladosporin resistant Dd2 line. A. Raw depth of coverage data for chromosome 13 from the CladoR_clone3, which contains a microarray-verified amplification conferring resistance to cladosporin [10]. B. Depth of coverage normalized after GC bias correction. C. Normalized depth of coverage after the Platypus smoothing and edge-calling algorithm, with the actual copy number prediction overlaid. D. Theoretical minimum detectable variant size for a range of total genome coverage. Deletions are easier to detect and can be identified with less total coverage and in smaller sizes. Similarly, 3x amplifications are easier to detect than 2x.

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