Table 2 SNP-miRNA pairs reported to disturb miRNA bindings by mrSNP for SNPs - miRNA couples obtained from miRdSNPs
From: mrSNP: Software to detect SNP effects on microRNA binding
(a) Pairs captured with the minimum matching criteria | |||||||
|---|---|---|---|---|---|---|---|
SNP | miRNA | Chr | Position | Alleles | Success | Explanation | |
rs8829 | hsa-miR-101 | 7 | 148504618 | C | A | ✓ | Binds one of the sequences with 8 consecutive matches. SNP breaks the match on 2nd position, min. match critera is not satisfied. |
rs28635788 | hsa-miR-124 | 2 | 47301624 | C | T | ✓ | Binds one of the sequences with 7 consecutive matches. SNP breaks the match on 2nd position, min. match critera is not satisfied. |
rs28381252 | hsa-miR-224 | 19 | 45976504 | C | T | ✓ | Binds one of the sequences with 7 consecutive matches. SNP breaks the match on 2nd position, min. match critera is not satisfied. |
rs11782817 | hsa-miR-144 | 8 | 57074233 | A | C | ✓ | Binds one of the sequences with 10 consecutive matches. SNP breaks the match on 2nd position, min. match critera is not satisfied. |
rs11550076 | hsa-miR-25 | 9 | 110247352 | A | G | ✓ | Binds one of the sequences with 7 consecutive matches. SNP breaks the match on 2nd position, min. match critera is not satisfied. |
rs10196117 | hsa-miR-124 | 2 | 47301624 | C | T | ✓ | Binds one of the sequences with 7 consecutive matches. SNP breaks the match on 2nd position, min. match critera is not satisfied. |
rs1143552 | hsa-miR-181b | 22 | 33256174 | A | G | ✓ | Binds one of the sequences with 8 consecutive matches. SNP breaks the match on the 3rd position, min. match critera is not satisfied. |
rs3733067 | hsa-miR-30a | 3 | 52290594 | A | G | ✓ | Binds one of the sequences with 7 consecutive matches. SNP breaks the match on 4th position, min. match critera is not satisfied. |
rs35180728 | hsa-miR-1 | 11 | 118473587 | - | T | ✓ | Binds one of the sequences with 7 consecutive matches. SNP breaks (deletes) the match on 4th position, min. match critera is not satisfied. |
rs11557771 | hsa-miR-218 | 14 | 69341243 | A | C | ✓ | Binds one of the sequences with 8 consecutive matches. SNP breaks the match on 6th position, min. match critera is not satisfied. |
rs10055 | hsa-miR-30a | 16 | 24835876 | T | C | ✓ | Binds one of the sequences with 8 consecutive matches. SNP breaks the match on 6th position, min. match critera is not satisfied. |
rs12635 | hsa-miR-197 | 19 | 14072442 | C | T | ✓ | Binds one of the sequences with 8 consecutive matches. SNP breaks the match on 6th position, min. match critera is not satisfied. |
rs3208684 | hsa-let-7g | 20 | 30252805 | T | G | ✓ | Binds one of the sequences with 7 consecutive matches. SNP breaks the match on the 6th position, min. match critera is not satisfied. |
rs3208684 | hsa-let-7c | 20 | 30252805 | T | G | ✓ | Binds one of the sequences with 7 consecutive matches. SNP breaks the match on the 6th position, min. match critera is not satisfied. |
rs5031032 | hsa-miR-1 | 12 | 102796132 | - | T | ✓ | Binds one of the sequences with 7 consecutive matches. SNP breaks (deletes) the match on 6th position, min. match critera is not satisfied. |
rs1063320 | hsa-miR-148a | 6 | 29798749 | C | G | ✓ | Binds one of the sequences with 8 consecutive matches. SNP breaks the match on the 7th position, min. match critera is not satisfied. |
rs1063320 | hsa-miR-148b | 6 | 29798749 | C | G | ✓ | Binds one of the sequences with 7 consecutive matches. SNP breaks the match on the 7th position, min. match critera is not satisfied. |
rs1063320 | hsa-miR-152 | 6 | 29798749 | C | G | ✓ | Binds one of the sequences with 7 consecutive matches. SNP breaks the match on the 7th position, min. match critera is not satisfied. |
rs12831 | hsa-miR-122 | 16 | 30081561 | A | C | ✓ | Binds one of the sequences with 8 consecutive matches. SNP breaks the match on 7th position, min. match critera is not satisfied. |
(b)Pairs captured with the minimum energy threshold | |||||||
SNP | miRNA | Chr | Position | Alleles | Success | Explanation | |
rs9266 | hsa-miR-181c | 12 | 25362217 | G | A | ✓ | Binds one of the sequences with 7 consecutive matches. SNP breaks the match on the 8th position (7th of seed), the binding energy (of 6mer) is lower than cut off. |
1434536 | hsa-miR-125b | 4 | 96075965 | T | C | ✓ | Binds one of the sequences with 8 consecutive matches. SNP breaks the match on the 8th position (7th of seed), the binding energy (of 6mer) is lower than cut off. |
rs17026326 | hsa-miR-19b | 3 | 30733356 | A | T | ✓ | Binds one of the sequences with 8 consecutive matches. SNP breaks the match on the 8th position (7th of seed), the binding energy (of 6mer) is lower than cut off. |
rs17026326 | hsa-miR-19a | 3 | 30733356 | A | T | ✓ | Binds one of the sequences with 8 consecutive matches. SNP breaks the match on the 8th position (7th of seed), the binding energy (of 6mer) is lower than cut off. |
rs3731562 | hsa-let-7d | 3 | 48199877 | G | A | ✓ | Binds one of the sequences with 8 consecutive matches. SNP introduces a GU wobble on 2nd position, the binding energy is lower than cut off. |
rs3731562 | hsa-let-7g | 3 | 48199877 | G | A | ✓ | Binds one of the sequences with 8 consecutive matches. SNP introduces a GU wobble on 2nd position, the binding energy is lower than cut off. |
rs3731562 | hsa-let-7c | 3 | 48199877 | G | A | ✓ | Binds one of the sequences with 8 consecutive matches. SNP introduces a GU wobble on 2nd position, the binding energy is lower than cut off. |
rs3731562 | hsa-let-7b | 3 | 48199877 | G | A | ✓ | Binds one of the sequences with 8 consecutive matches. SNP introduces a GU wobble on 2nd position, the binding energy is lower than cut off. |
rs3731562 | hsa-let-7a | 3 | 48199877 | G | A | ✓ | Binds one of the sequences with 8 consecutive matches. SNP introduces a GU wobble on 2nd position, the binding energy is lower than cut off. |
rs1051780 | hsa-miR-34a | 17 | 8063056 | C | T | ✓ | Binds one of the sequences with 7 consecutive matches. SNP introduces a GU wobble on 2nd position, the binding energy is lower than cut off. |
rs59564714 | hsa-miR-15a | 11 | 73686038 | A | G | ✓ | Binds one of the sequences with 7 consecutive matches. SNP introduces a GU wobble on 3rd position, the binding energy is lower than cut off. |
rs16952445/rs1138624 | hsa-miR-122 | 16 | 30081565 | C | T | ✓ | Binds one of the sequences with 7 consecutive matches. SNP introduces a GU wobble on 3rd position, the binding energy is lower than cut off. |
rs1801938 | hsa-miR-1 | 19 | 2101071 | T | G | ✓ | Binds one of the sequences with 7 consecutive matches. SNP introduces a GU wobble on 3rd position, the binding energy is lower than cut off. |
rs6875894 | hsa-miR-135b | 5 | 112179965 | C | T | ✓ | Binds one of the sequences with 9 consecutive matches. SNP introduces a GU wobble on 4th position, the binding energy is lower than cut off. |
rs6875894 | hsa-miR-135a | 5 | 112179965 | C | T | ✓ | Binds one of the sequences with 9 consecutive matches. SNP introduces a GU wobble on 4th position, the binding energy is lower than cut off. |
rs73306851 | hsa-miR-125b | 17 | 38327577 | A | G | ✓ | Binds one of the sequences with 7 consecutive matches. SNP introduces a GU wobble on 5th position, the binding energy is lower than cut off. |
rs11552766 | hsa-miR-185 | 3 | 49396652 | A | G | ✓ | Binds one of the sequences with 8 consecutive matches. SNP introduces a GU wobble on 5th position, the binding energy is lower than cut off. |
rs2664575 | hsa-miR-17 | 20 | 47862478 | G | T | ✓ | Binds one of the sequences with 7 consecutive matches. SNP breaks the match on the 6th position. |
rs10187 | hsa-miR-210 | 12 | 108962804 | C | T | ✓ | Binds one of the sequences with 7 consecutive matches. SNP introduces a GU wobble on 7th position, the binding energy is lower than cut off. |
midrule rs70965446 | hsa-miR-141 | 4 | 56301355 | A | G | ✓ | Binds one of the sequences with 9 consecutive matches. SNP introduces a GU wobble on 7th position, the binding energy is lower than cut off. |
rs8226 | hsa-miR-124 | 22 | 36677414 | G | A | ✓ | Binds one of the sequences with 7 consecutive matches. SNP introduces a GU wobble on 7th position, the binding energy is lower than cut off. |
rs35122558 | hsa-miR-155 | 7 | 32908099 | C | T | ✓ | Binds one of the sequences with 7 consecutive matches. SNP introduces a GU wobble on 8th position, the binding energy is lower than cut off. |
rs55774542 | hsa-miR-125b | 12 | 48238167 | A | G | ✓ | Binds one of the sequences with 7 consecutive matches. SNP introduces a GU wobble on 8th position, the binding energy is lower than cut off. |
rs59628511 | hsa-miR-124 | 9 | 140509654 | C | G | ✓ | Binds one of the sequences with 8 consecutive matches. SNP introduces a GU wobble on 8th position, the binding energy is lower than cut off. |