Table 4 SNP-miRNA pairs not predicted to disturb the miRNA bindings by mrSNP on the SNPs - miRNA couples obtained from miRdSNP because neither SNP allele is predicted to bind the miRNAs
From: mrSNP: Software to detect SNP effects on microRNA binding
SNP | miRNA | Chr | Position | Alleles | Success | Explanation | |
|---|---|---|---|---|---|---|---|
rs16952475 | hsa-miR-185 | 15 | 69018917 | C | T | × | miRNA is predicted not to bind neither of the sequences. There are 6 consecutive matches, the binding energy is lower than cut off. The SNP further introduces GU wobble on 5th position. |
rs17168525 | hsa-let-7b | 7 | 135613262 | A | G | × | miRNA is predicted not to bind neither of the sequences. There are 6 consecutive matches, the binding energy is lower than cut off. The SNP further introduces GU wobble on 5th position. |
rs1802677 | hsa-miR-181b | 22 | 33258866 | A | T | × | miRNA is predicted not to bind neither of the sequences. There are 6 consecutive matches, the binding energy is lower than cut off. The SNP further breaks the match on 4th position. |
rs56165498 | hsa-miR-29a | 15 | 68595075 | A | C | × | miRNA is predicted not to bind neither of the sequences. There are 6 consecutive matches, the binding energy is lower than cut off. The SNP further breaks the match on 5th position. |
rs57321187 | hsa-miR-192 | 10 | 79550563 | C | T | × | miRNA is predicted not to bind neither of the sequences. There are 6 consecutive matches, the binding energy is lower than cut off. The SNP further breaks the match on 6th position. |
rs62062994 | hsa-miR-29b | 17 | 48261978 | G | T | × | miRNA is predicted not to bind neither of the sequences. There are 6 consecutive matches, the binding energy is lower than cut off. The SNP further breaks the match on 3rd position. |
rs62062994 | hsa-miR-29c | 17 | 48261978 | G | T | × | miRNA is predicted not to bind neither of the sequences. There are 6 consecutive matches, the binding energy is lower than cut off. The SNP further breaks the match on 3rd position. |
rs7233791 | hsa-miR-124 | 18 | 47309884 | C | G | × | miRNA is predicted not to bind neither of the sequences. There are 6 consecutive matches, the binding energy is lower than cut off. The SNP further breaks the match on 5th position. |
rs73954984 | hsa-miR-17 | 2 | 111925932 | C | T | × | miRNA is predicted not to bind neither of the sequences. There are 6 consecutive matches, the binding energy is lower than cut off. The SNP further breaks the match on 7th position. |
rs1804734 | hsa-miR-21 | 1 | 203278606 | A | G | × | miRNA is predicted not to bind neither of the sequences. There are 7 consecutive matches with a GU wobble, the binding energy is lower than cut off. The SNP further breaks the match on 6th position. |
rs3802782 | hsa-let-7b | 11 | 69468919 | T | C | × | miRNA is predicted not to bind neither of the sequences. There are 7 consecutive matches with a GU wobble, the binding energy is lower than cut off in both. The SNP is on 11th position, it further reduces the binding energy. |
rs3218074 | hsa-miR-503 | 19 | 30315176 | A | G | × | miRNA is predicted not to bind neither of the sequences. There are 7 consecutive matches with a GU wobble, the binding energy is lower than cut off. The SNP further introduces GU wobble on 1st position. |
rs1803045 | hsa-miR-1 | 12 | 49330252 | C | T | × | miRNA is predicted not to bind neither of the sequences. There are 6 consecutive matches with a GU wobble, min. match criteria cannot be satisfied in both. The SNP is on 12th position, it further reduces the binding energy. |