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Figure 3 | BMC Bioinformatics

Figure 3

From: Predicting HIV-1 broadly neutralizing antibody epitope networks using neutralization titers and a novel computational method

Figure 3

Predicted Epitope Networks for all mAbs in 3D. Predicted epitope networks are indicated in red for each antibody. The 3D models represent a theoretical view of full-length HXB2 gp120 monomer by the CPHmodels program [46]. Model is rotated for each antibody to show the best view of network residues. Visualizations were generated using UCSF Chimera [49]. INSET: General location of the variable regions V1, V2, and V3 are indicated. Notably, the most overlapping residues between the predicted epitope networks of different mAbs were predominantly located within the variable loops V1/V2 of gp120.

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