Figure 8

Deciding where to place the cutoff using synthetic data. a) Sorted squared characteristic direction components for the various synthetic datasets. Dashed lines indicate the top 500, 1000, and 2000 genes. b) The null ranked squared coefficient distribution for the synthetic datasets. c) The ratio of the ranked squared coefficient distribution for the synthetic datasets to the null distribution assuming no difference between the classes. Dashed lines indicate the top 500, 1000, and 2000 genes. d) The cumulative distribution of the ratio between the squared coefficient distribution and the null distribution. The variable, s, which is indicated with an arrow, measures the distance perpendicular to the diagonal. e) The value of s for each of the synthetic datasets. The dashed lines indicate the top 500, 1000, and 2000 genes.