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Table 4 A comparison of GraphPAC and NMC identified clusters for the BRAF structure

From: A graph theoretic approach to utilizing protein structure to identify non-random somatic mutations

(a) Clusters found by GraphPAC
    p-value
Start End # Muts. GraphPAC NMC
600 600 60 2.12E-129 2.12E-129
597 600 62 1.49E-104 1.49E-104
600 601 62 1.49E-104 9.22E-117
596 600 64 7.16E-102 7.16E-102
596 601 66 3.37E-91 1.16E-100
597 601 64 8.07E-91 7.16E-102
601 671 3 5.85E-38 -
600 671 63 8.30E-37 7.08E-26
469 601 72 2.59E-22 5.92E-17
581 601 68 1.23E-21 1.33E-65
581 600 66 2.94E-20 3.13E-63
469 600 70 3.98E-20 4.91E-15
466 601 74 2.15E-17 9.69E-19
466 600 72 7.01E-16 1.60E-16
464 601 75 1.15E-15 1.12E-19
464 600 73 2.33E-14 2.97E-17
(b) Clusters found by NMC and dropped by GraphPAC
Start End # Muts.   NMC Pvalue
596 671 67   4.12E-29
597 671 65   4.79E-27
581 671 69   3.33E-26
464 671 76   5.92E-09
466 671 75   3.32E-08
469 671 73   8.11E-07
  1. A "-" for the NMC value signifies that cluster was not identified under the linear algorithm.