Figure 5

Proportion of true positives among unique discoveries. Proportion of true positives among unique discoveries for DESeq with a fixed study effect (orange bars) and Fisher (red bars). Each barplot represents the results of a particular setting, with columns corresponding (from left to right) to simulations including 2 studies, 3 studies, and 5 studies, and rows corresponding (from top to bottom) to simulations with inter-study variability set to σ = 0.15 and σ = 0.50 (low inter-study variability to large inter-study variability). Error bars represent one standard deviation, and numbers in parentheses represent the mean total number of unique discoveries for DESeq with study effect as compared to Fisher and vice versa, respectively.