An example of LAD
profile alignment for a non-homologous protein pair. Owing to conformations of both structures are significantly different, their LADED profiles could not be aligned properly, and therefore resulted in a high LAD
. (a) Cartoon representation for the non-homologous protein pair of 1wwa:X (green) and 1k0y:C (blue). (b) The pairwise alignment result of LADED profiles for both structures. The x-axis represents the serial numbers of residue pair and the y-axis denotes LAD values.