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Table 2 QCMF-significant essential sites in the human GCK protein, which are nearby either nsSNPs or strictly conserved sites

From: Quantum coupled mutation finder: predicting functionally or structurally important sites in proteins using quantum Jensen-Shannon divergence and CUDA programming

QCMF-significant Nearby nsSNPs or strictly Reference
essential sites conserved sites  
M37 36s,39s,40s [38, 39, 43, 51]
S76 147c  
L79 78c,80c,150c -
T82 81c -
N83 81c,108s,110s [43, 51]
V86 85c,106s [38]
S127 130s [40]
F148 147c,150c,s [38, 39, 43, 51]
F152 150c,s, 151c [39, 43, 51]
P153 154s [39]
H156 154s [39]
A176 119s,175s [43]
G178 164c  
N180 162s,182s [38, 39, 43],
L185 182s,188s [39, 43, 51]
A201 147c,453c  
M202 147c,203s [43]
A232 223s,231c [39, 40, 51]
C233 223s,234c,235c [39, 40, 51]
V253 234c,254c  
F260 257s,258c,259s,261s [39, 43]
L271 274c  
V277 274c,278c,279s [43]
S281 278c,279s [43]
Y297 291c,295c,299c, 300s [43]
M298 295c,299c,300s [43]
T332 295c,299c  
V374 377c  
A378 377c,382s [43]
A379 377c,382s [43]
S383 382s,385s [43]
A384 382s,385s [43]
A387 385s [43]
S388 385s,392s [38, 43]
V412 226s,227c,410c,414s,416s [40, 43]
F419 416s [40]
E443 444c,445c,447s [39]
G446 444c,445c,447s,448c,449c [39]
  1. s: non-synonymous snp site, c: strictly conserved site.