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Table 1 Experimentally validated true and false positive hits from dataset 1

From: TOPS: a versatile software tool for statistical analysis and visualization of combinatorial gene-gene and gene-drug interaction screens

Model (pvalue) True positives False positives Unverified
LM (pvA) 8 2 40
LM (pvB) 1 1 48
LM (pvAll) 6 2 42
sLM (pvA) 8 2 40
sLM (pvB) 2 0 48
sLM (pvAll) 8 1 41
UT (pvA) 7 2 41
UT (pvB) 4 2 44
UT (pvAll) 6 2 42
  1. The top 50 interactions from a ranked hit list are categorized by experimentally validated as true or false positive. Hits that were not experimentally tested are indicated as "unverified". The true and false positive rates for the linear model (LM), split linear model (sLM) or U-Test (UT) algorithms for either p-value A (pvA), p-value B (pvB) or the combined p-value (pvAll) are shown.