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Figure 6 | BMC Bioinformatics

Figure 6

From: Reducing bias in RNA sequencing data: a novel approach to compute counts

Figure 6

Data variance and coefficient of variation. Variance and coefficient of variation (CV) of Jiang's data: variance vs. mean of log-counts/RPKMs (left plots) and CV vs. log-mean of counts/RPKMs (right plots). Curves represent cubic-spline fits computed on variance/CV, averaged in bins of 5000 exons each. Since maxcounts, totcounts, and totcounts normalized with RPKM (RPKM) and within-lane full-quantile normalization over exon length (FullQ) approaches are compared, x-values are scaled to cover the range [0, 1] in order to make them comparable.

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