Figure 7

Differences between the agonist's and antagonist's conformations. The differences of residues 338-340 (loop linking helix 2 and helix 3) and 532-548 (end of helix 11 to end of helix 12) are shown in the five pairs of protein conformations as mentioned in Figure 6. Color codes: 1QKT (orange), 2QA8 (blue), 2QGT (pink), 2Q6J (orange red), 3DT3 (green) and 1XP1 (light green). The cognate ligands of these structures were also shown using the same color codes.