|
Agonist
|
Antagonist
|
---|
|
SDM
|
Huang et al.
|
SDM
|
Huang et al .
|
---|
1%
|
20.5
|
19.2
|
12.7
|
12.7
|
2%
|
17.9
|
-
|
21.6
|
-
|
3%
|
14.8
|
-
|
17.8
|
-
|
4%
|
13.9
|
-
|
15.3
|
-
|
5%
|
12.1
|
-
|
12.2
|
-
|
20%
|
3.8
|
4.5
|
3.2
|
1.3
|
Max
|
39.4
|
29.6
|
21.8
|
101.6*
|
- Comparisons of the calculated EFs at different % of database screened and EFmax for the SDMs reported in our work and Huang et al.[44]. *The remarkably high EFmax reported by Huang et al. for antagonist may require further verification.