| | Agonist | Antagonist |
|---|
| | SDM | CDA | SDM | CDA |
|---|
1% | 20.5 | 23.6 | 12.7 | 12.7 |
2% | 17.9 | 19.3 | 21.6 | 21.6 |
3% | 14.8 | 14.8 | 17.8 | 17.8 |
4% | 13.9 | 12.7 | 15.3 | 15.3 |
5% | 12.1 | 10.3 | 12.2 | 12.2 |
20% | 3.8 | 3.1 | 3.2 | 3.2 |
Max | 39.4 | 23.6 | 21.8 | 21.6 |
- Comparisons of the calculated EFs at different % of database screened and EFmax for the SDMs and CDA. For agonist screening, CDA performs better at the early stage (1-3%) compared to SDM. For antagonist screening, comparable results are obtained. The EFmax for the SDMs are better than the CDA, however, these peaks occur at a later stage of screening.
