BMC Bioinformatics

Table 1 Atoms of amino acids involved in H-bonding interactions with nucleic acids.

From: DBBP: database of binding pairs in protein-nucleic acid interactions

		RNA-protein complex			DNA-protein complex
AA	Atom	Acceptor	Donor	#H-bonds	Acceptor	Donor	#H-bonds
Ala	N		1,069	1,653		674	808
	O	567			134
	OXT	17
Arg	NH2		9,252	22,395		6,144	13,705
	NH1		7,278			4,665
	NE		4,011			2,191
	N		1,388			606
	O	455			99
	OXT	13
Asn	ND2		3,268	4,953		2349	3,119
	OD1	934			408
	N		549			261
	O	202			101
Asp	OD2	1,416		2,829	353		735
	OD1	1,183			290
	O	178			31
	N		52			61
Cys	SG	23	76	125	19	120	215
	O	24
	N		2			76
Gln	NE2	168	2496	4,468	2	1,593	2,571
	OE1	1,108			363	521
	N		480
	O	216			92
Glu	OE2	1,691		3,507	275		737
	OE1	1,315			260
	O	193			19
	N		308			183
Gly	N		1,518	2,699		1749	1,902
	O	1,175			153
	OXT	6
His	NE2	412	1,454	3,591	30	768	1,254
	ND1	536	1,014		15	327
	N		106			90
	O	69			24
Ile	N		258	309		433	466
	O	40			33
	OXT	11
Leu	N		507	766		362	387
	O	259			25
Lys	NZ		9,864			5,145	6,351
	N		852	11,436	86	1,120
	O	717
	OXT	3
Met	SD	105		662	15		147
	O	276			13	119
	N		278
	OXT	3
Phe	O	333		539	42		247
	N		206			205
Pro	O	161		161	28		28
Ser	OG	1,179	4,675	6,997	182	3,533	4,741
	N		683			958
	O	460			68
Thr	OG1	1,058	4,406	7,267	158	3,017	4,252
	O	750			132
	N		1,053			945
Trp	NE1		532	582		358	393
	OXT	16
	O	14			10
	N		20			25
Tyr	OH	597	1,935	2,682	133	1,800	2,511
	O	93			28
	N		57			550
Val	O	174		326	36		386
	N		151			350
	OXT	1
		18,151	59,796	77,947	3,657	41,298	44,955

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ISSN: 1471-2105

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