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Table 1 Results of MT applied to three short-read alignment programs (BWA, Bowtie and Bowtie2) ran on the paired-end sequencing simulated reads of varying number.

From: Verification and validation of bioinformatics software without a gold standard: a case study of BWA and Bowtie

MRs

103

104

105

106

107

BWA

MR1

F

F

F

F

F

MR2

F

F

F

F

F

MR3

F

F

F

F

F

MR4

 

F

F

F

F

MR5

F

F

F

F

F

MR6

     

MR7

   

F

F

MR8

     

MR9

     

Bowtie

MR1

 

MR2

F

F

F

F

F

MR3

     

MR4

     

MR5

F

F

F

F

F

MR6

     

MR7

     

MR8

F

F

F

F

F

MR9

     

Bowtie2

MR1

 

MR2

F

F

F

F

F

MR3

     

MR4

     

MR5

F

F

F

F

F

MR6

     

MR7

     

MR8

F

F

F

F

F

MR9

     
  1. F (Failure).