Table 1 Examples of the pathology similarities for 4 pathological findings.
From: An integrative model of multi-organ drug-induced toxicity prediction using gene-expression data
| Â | Liver Change, eosinophilic | Liver Cellular infiltration | Kidney Vacuolization, cytoplasmic | Kidney Regeneration |
|---|---|---|---|---|
Liver Change, eosinophilic | 1.00 | 0.21 | 0.05 | 0.00 |
Liver Cellular infiltration | 0.21 | 1.00 | 0.02 | 0.04 |
Liver Hypertrophy | 0.04 | 0.10 | 0.08 | 0.12 |
Liver Degeneration | 0.00 | 0.20 | 0.00 | 0.10 |
Liver Deposit, pigment | 0.02 | 0.05 | 0.00 | 0.02 |
Liver Increased mitosis | 0.08 | 0.04 | 0.00 | 0.02 |
Liver Necrosis | 0.05 | 0.32 | 0.03 | 0.05 |
Liver Single cell necrosis | 0.04 | 0.20 | 0.00 | 0.06 |
Liver Vacuolization, cytoplasmic | 0.05 | 0.00 | 0.14 | 0.08 |
Liver Proliferation | 0.04 | 0.14 | 0.08 | 0.07 |
Liver Fibrosis | 0.00 | 0.15 | 0.05 | 0.04 |
Kidney Cellular infiltration | 0.00 | 0.01 | 0.00 | 0.11 |
Kidney Hypertrophy | 0.00 | 0.02 | 0.00 | 0.04 |
Kidney Degeneration | 0.04 | 0.04 | 0.09 | 0.29 |
Kidney Necrosis | 0.10 | 0.02 | 0.11 | 0.16 |
Kidney Hyaline droplet | 0.01 | 0.00 | 0.05 | 0.10 |
Kidney Cast, hyaline | 0.02 | 0.02 | 0.19 | 0.11 |
Kidney Dilatation | 0.04 | 0.01 | 0.05 | 0.16 |
Kidney Change, basophilic | 0.02 | 0.02 | 0.03 | 0.00 |
Kidney Vacuolization, cytoplasmic | 0.05 | 0.02 | 1.00 | 0.03 |
Kidney Regeneration | 0.00 | 0.04 | 0.03 | 1.00 |