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Table 5 Amino acid classification according to their physiochemical properties.

From: Protein inter-domain linker prediction using Random Forest and amino acid physiochemical properties

Peoperty

Value

Amino acids

Charge

Positive

H, K, R

 

Negative

D, E

 

Neutral

A, C, F, G, I, L, M, N, P, Q, S, T, V, W, Y

Polatity

Polar

C, D, E, H, K, N, Q, R, S, T, Y

 

Non-polar

A, F, G, I, L, M, P, V, W

Aromaticity

Aliphatic

I, L, V

 

Aromatic

F, H, W, Y

 

Neutral

A, C, D, E, G, K, M, N, P, Q, R, S, T

Size

Small

A, G, P, S

 

Medium

D, N, T

 

Large

C, E, F, H, I, K, L, M, Q, R, V, W, Y,

Electronic

Strong donor

A, D, E, P

 

Weak donor

I, L, V

 

Neutral

C, G, H, S, W

 

Weak acceptor

F, M, Q, T, Y

 

Strong acceptor

K, N, R