Automatic classification of protein structures using low-dimensional structure space mappings

BMC Bioinformatics

Table 4 Classification performance within selected SCOP superfamilies.

Superfamily	"Winged-helix"	PH domain-like	NTF2-like	Ubiquitin-like	Immunoglobin
Precision	0.997	1	1	1	0.987
Recall	0.766	0.818	0.982	0.909	0.811
F ₁ -measure	0.866	0.900	0.991	0.953	0.890

Classification performance statistics are given for each of the five superfamilies shown in Figure 6. Prediction of SCOP superfamily membership is made by thresholding MPSS distances from FATCAT(C3) with the (single) optimum threshold obtained from ROC analysis. Statistics presented in the table include: precision or positive predictive value, recall or true positive rate, and the F₁-measure, which is the harmonic mean of precision and recall.

ISSN: 1471-2105