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Figure 10 | BMC Bioinformatics

Figure 10

From: Transcriptional regulation prediction of antiestrogen resistance in breast cancer based on RNA polymerase II binding data

Figure 10

Motifs of the same TF in all of different areas showed different patterns of regulation. The horizontal axis represents different intervals, and the vertical axis represents regression coefficient, which reflects the signal intensities of the regulatory TFs. The order of logos corresponds to the respective motif. In OHT cells, motifs of AR in both TSS -400 bp ~ +300 bp and TSS -600 bp ~ +200 bp were different. The ER and IRF motifs even exhibited a regulation change in direction. In particular, the regulatory patterns of Evi-1 over the entire range were nearly opposite while their motifs were very similar.

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