Transcriptional regulation prediction of antiestrogen resistance in breast cancer based on RNA polymerase II binding data

Table 1 A summary of differentially regulated genes, regulatory TFs and verified TFs identified from MCF7 and OHT cells.

	MCF7			OHT
	Based on gene expression data	Based on PolII binding quantity data	Results compared between PolII data and gene expression data	Based on gene expression data	Based on PolII binding quantity data	Results compared between PolII data and gene expression data
Differentially regulated genes	116	292	+ 176	133	386	+ 253
Identified regulatory TFs	20	41	+ 21	30	48	+ 18
Verified TFs in prediction	9	22	+ 13	8	25	+ 17
All verified TFs	186	186	-----	184	184	-----

ISSN: 1471-2105