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Table 1 Experiment generation (simulation) and the nominal value.

From: Biochemical systems identification by a random drift particle swarm optimization approach

P

0.05

0.13572

 

0.36840

1.0

S

0.1

0.46416

 

2.1544

10

Parameter

Element of decision variables vector

Nominal value

Parameter

Element of decision variables vector

Nominal value

V 1

θ 1

1

V 4

θ 19

0.1

Ki 1

θ 2

1

K 4

θ 20

1

ni 1

θ 3

2

k 4

θ 21

0.1

Ka 1

θ 4

1

V 5

θ 22

0.1

na 1

θ 5

2

K 5

θ 23

1

k 1

θ 6

1

k 5

θ 24

0.1

V 2

θ 7

1

V 6

θ 25

0.1

Ki 2

θ 8

1

K 6

θ 26

1

ni 2

θ 9

2

k 6

θ 27

0.1

Ki 2

θ 10

1

kcat 1

θ 28

1

na 2

θ 11

2

Km 1

θ 29

1

k 2

θ 12

1

Km 2

θ 30

1

V 3

θ 13

1

kcat 2

θ 31

1

Ki 3

θ 14

1

Km 3

θ 32

1

ni 3

θ 15

2

Km 4

θ 33

1

Ka 3

θ 16

1

Kcat 3

θ 34

1

na 3

θ 17

2

Km 5

θ 35

1

k 3

θ 18

1

Km 6

θ 36

1

  1. (P and S are initial concentrations of the pathway substrate and product, and were varied and combined to generate a total of 16 sets of pseudo-experimental (simulation) measurements)