Table 6 Clusters obtained by k-means algorithm with training set mode and k = 4
From: Knowledge discovery of drug data on the example of adverse reaction prediction
Attribute | Cluster1 | Cluster2 | Cluster3 | Cluster4 |
|---|---|---|---|---|
Age | 14.5 | 14.0 | 16.0 | 16.0 |
Age of ARA | 5.0 | 6.0 | 0.4 | <1 |
Type of antibiotic | cef&pen | pen | fenoksi | ampicillin |
Severity reaction | skin | skin | skin | skin |
Age of the 1st antibiotic use (y) | 5.0 | <1 | <1 | <1 |
Other allergic disease (skin) | yes | no | no | yes |
Other allergic disease (rhinitis) | no | no | no | no |
Other allergic disease (bronchitis) | no | no | no | yes |
Other allergic disease (asthma) | no | no | no | no |
Blood test on allergy - IgE | positive | positive | positive | positive |
Perinatal disorders | yes | no | no | yes |
Birth order | 1 | 1.379 | 1.2828 | 1.2685 |
Severe respiratory disease | yes | no | no | Yes |
Age of severe respiratoy disease | 1.5 | 6.0 | 6.0 | 6.0 |
Otitis media | yes | yes | no | Yes |
Age of otitis media | 9.0 | <1 | <1 | <1 |
Other infections | yes | yes | yes | Yes |
Other infections | 1X | 2X | 2X | 2X |
Varicella | yes | no | yes | no |
Age of varicella | 7.5 | 3.0 | 3.0 | 3.0 |
Hospitalization <2y of age | no | no | no | no |
Number of infections per year | 3-4X | 2-3X | 2-3X | 3X |
Antibiotic exposure before ARA | 2X | 1X | 1X | 1X |
Family history on ARA | negative | negative | negative | positive |
Allergic diseases in family | no | no | no | no |
Chr diseases diseases in family | no | no | no | no |