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Table 1 Accuracy of Bowtie and ADaM as the error rate changes from 1x through 10x (1x being a typical Illumina error rate, and 10x is ten times that).

From: ADaM: augmenting existing approximate fast matching algorithms with efficient and exact range queries

 

1x

2x

10x

 

%Acc

RunTime

%Acc

RunTime

%Acc

RunTime

Bowtie

95.9

11.9s

93.5

11.6s

62.2

5.48s

ADaM+Bowtie

99.6

46.7 m

99.1

56.0 m

90.6

37.0 h

  1. Note that, even at high error, the combined approach still maintains high accuracy.