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Table 1 Signal-to-noise ratio, weight and proportion of different types of seed matches in different regions.

From: Identifying microRNA targets in different gene regions

 

2t8A1

2t8

2t7A1

2t7

1t8GU

 

Number of matches (miRWalk)

1,235

3,105

2,657

7,296

3,734

Promoters

 

171

628

463

1,594

730

5'UTRs

 

1,153

3,116

2,729

6,494

3,343

CDSs

 

2,366

4,103

3,204

6,920

3,797

3'UTRs

Number of matches (Average of 50 times random shuffle)

911

2,639

2,422

7,014

3,068

Promoters

 

141

489

391

1,415

547

5'UTRs

 

904

2,331

2,331

5,997

2,655

CDSs

 

1,069

2,593

2,513

6,060

3,175

3'UTRs

Signal-to-noise ratio

1.355

1.177

1.097

1.040

1.217

Promoters

 

1.213

1.284

1.184

1.126

1.333

5'UTRs

 

1.275

1.337

1.171

1.083

1.259

CDSs

 

2.214

1.583

1.275

1.142

1.196

3'UTRs

Weight

0.293

0.146

0.080

0.033

0.179

Promoters

 

0.176

0.234

0.151

0.104

0.275

5'UTRs

 

0.227

0.277

0.141

0.068

0.214

CDSs

 

1.000

0.480

0.227

0.117

0.161

3'UTRs

Proportion (miRWalk)

7%

17%

15%

40%

21%

Promoters

 

5%

18%

13%

44%

20%

5'UTRs

 

7%

19%

16%

39%

20%

CDSs

 

12%

20%

16%

34%

19%

3'UTRs

Proportion (Average of 50 times shuffle)

6%

16%

15%

44%

19%

Promoters

 

5%

16%

13%

47%

18%

5'UTRs

 

6%

16%

16%

42%

19%

CDSs

 

7%

17%

16%

39%

21%

3'UTRs

  1. The number of matches in miRWalk dataset is the real number of each seed match type in each target region. The number of matches from random shuffles is the average number of each type of seed match over 50 randomly shuffled mRNA sequences. The signal-to-noise ratio is the ratio of these two numbers. The weight is then calculated via the equation (1). The proportion is the percentage of a specific seed match type in each target region.