Mitochondrial genomic variation associated with higher mitochondrial copy number: the Cache County Study on Memory Health and Aging

Table 2 Demographic information for significant contrasts.

	Individuals/Missing	p-value¹		p-value²		Age	Male/Female	Mean copy #
		Nominal	Corrected	Nominal	Corrected
Whole network	1007/193	N/A	N/A	N/A	N/A	75.6	442/565	2.69
Branch 124	17/3	0	6.0e-4	0	8.0e-4	75.2	9/8	3.81
Branch 121	10/1	0	0.002	1.0e-4	0.0043	76.3	4/6	4.01
Branch 50	15/3	2.0e-4	0.017	2.0e-4	0.015	78.4	7/8	3.64

Here we report demographic information for each of the significant contrasts and for all the individuals in the dataset. The clade represented by Branch 121 is wholly contained within Branch 124, so these two contrasts represent a single effect. Branches 124 and 50 represent separate effects. Missing refers to the number of individuals for whom we have no mtDNA copy number measurement.¹p-values were calculated controlling only for the other significant branches ²p-values were calculated using age, gender, mtDNA copy number family risk score, and the other significant effects as covariates

ISSN: 1471-2105