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Table 2 SCOP SVM Classification Results.

From: Exploring representations of protein structure for automated remote homology detection and mapping of protein structure space

 

Fragbag Representation

Topic-Based Representation

SCOP Superfamily

Acc. (%)

TPR

FPR

AUC

Acc. (%)

TPR

FPR

AUC

P-Loop Binding

96.4

0.98

0.05

0.95

84.3

0.97

0.29

0.84

Immunoglobin

100.0

1.00

0.00

1.000

99.9

0.99

0.0

1.0

NAD(P)-binding Rossman

98.7

0.99

0.02

0.99

90.9

0.94

0.13

0.91

Thioredoxin-like

98.8

0.98

0.01

0.99

80.2

0.92

0.32

0.80

alpha/beta Hydrolases

99.1

1.00

0.02

0.99

92.7

0.95

0.10

0.93

EF-hand

100.0

1.00

0.00

1.000

98.8

0.99

0.01

0.99

Winged helix DNA-binding

98.7

0.98

0.01

0.99

84.4

0.79

0.11

0.84

  1. Performance is reported for the 7 SVM classifiers identifying a protein domain as being a member of one of the seven SCOP superfamilies. Accuracy (Acc.) is the sum of true positives and true negatives divided by the number of samples. Reported values are rounded up after the second decimal sign.