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Table 3 Cancer Genetics task event types and their arguments.

From: Overview of the Cancer Genetics and Pathway Curation tasks of BioNLP Shared Task 2013

Type Core arguments Additional arguments
Anatomical   
  DEVELOPMENT Theme (Anatomy)  
  BLOOD VESSEL DEVELOPMENT Theme?(Anatomy) AtLoc?
  GROWTH Theme (Anatomy)  
  DEATH Theme (Anatomy)  
  CELL DEATH Theme?(Cell)  
  BREAKDOWN Theme (Anatomy)  
  CELL PROLIFERATION Theme (Cell)  
  CELL DIVISION Theme (Cell)  
  CELL DIFFERENTIATION Theme (Cell) AtLoc?
  REMODELING Theme (Tissue)  
  REPRODUCTION Theme (Organism)  
Pathological   
  MUTATION Theme (GGP) AtLoc?, Site?
  CARCINOGENESIS Theme?(Anatomy) AtLoc?
  CELL TRANSFORMATION Theme (Cell) AtLoc?
  METASTASIS Theme?(Anatomy) ToLoc
  INFECTION Theme?(Anatomy), Participant?(Organism)  
Molecular   
  METABOLISM Theme (Molecule)  
    SYNTHESIS Theme (Simple chemical)  
    CATABOLISM Theme (Molecule)  
      AMINO ACID CATABOLISM Theme?(Molecule)  
      GLYCOLYSIS Theme?(Molecule)  
    GENE EXPRESSION Theme+(GGP)  
      TRANSCRIPTION Theme (GGP)  
      TRANSLATION Theme (GGP)  
      PROTEIN PROCESSING Theme (GGP)  
  PHOSPHORYLATION Theme (Molecule) Site?
(other chemical modifications defined similarly to Phosphorylation)
  PATHWAY Participant (Molecule)  
General   
  BINDING Theme+(Molecule) Site?
  DISSOCIATION Theme (Molecule) Site?
  LOCALIZATION Theme+(Molecule) At/From/ToLoc?
Regulation Theme (Any), Cause?(Any)  
  POSITIVE REGULATION Theme (Any), Cause?(Any)  
  NEGATIVE REGULATION Theme (Any), Cause?(Any)  
PLANNED PROCESS Theme*(Any), Instrument*(Entity)  
  1. The indentation corresponds to ontological structure (is-a/part-of relations). The suffixes ?, *, and + denote zero or one, zero or more, and one or more arguments of the shown type (respectively). GGP stands for Gene or gene product. For brevity, additional argument types are not shown in table: the AtLoc, FromLoc and ToLoc arguments take an anatomical entity type, and Site arguments take a Protein domain or region or DNA domain or region entity type.