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Figure 4 | BMC Bioinformatics

Figure 4

From: GRAPHIE: graph based histology image explorer

Figure 4

Morphology zebrafish retina case study. (a) Initial graph visualization. (b) Example phenotypes of the zebrafish retina: (red) retina of a mutant zebrafish. The mutant possess a small lens and fissure closure defect. (blue) Eye of wild-type zebrafish. Normal retinal lamination and a fused ventral fissure can be seen. (c) Graph created with selected features: the resulting graph shows better separation between wild-type and mutant-type zebrafish eye images, also helps users to spot the mis-annotated images. Here, we show three mis-annotated examples, with the upper two images were mis-annotated as wild-type and lower image being mis-annotated as mutant.

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