Protein complex detection in PPI networks based on data integration and supervised learning method

BMC Bioinformatics

Table 8 The F-score performances of SLPC on original PPI networks with different integrating thresholds.

int_thred	DIP	Krogan	Gavin	Avg.Δ
Origin	0.5531	0.5029	0.6389
0	0.5543	0.5298	0.6518	2.53%
-0.1	0.5463	0.5348	0.6665	3.14%
-0.2	0.5481	0.5382	0.6658	3.44%
-0.3	0.5621	0.5515	0.6623	4.98%
-0.4	0.5527	0.5485	0.6642	4.32%
-0.5	0.5577	0.544	0.6638	4.30%
-0.6	0.553	0.5543	0.665	4.76%
-0.7	0.5418	0.5355	0.6638	2.78%
-0.8	0.5409	0.5329	0.6685	2.80%
-0.9	0.5335	0.5471	0.6694	3.34%
-1.0	0.5224	0.5445	0.6511	1.54%
-1.1	0.5138	0.5403	0.6501	0.69%
-1.2	0.5166	0.5368	0.6487	0.56%

#int_thred. denotes the different integrating thresholds; Avg.Δ denotes the average F-score improvement over that on the original PPI networks.

ISSN: 1471-2105