Figure 2

Kernel density and scatter plot (key genes only). Gaussian kernel density plot and a paired scatter plot for Presentation (A) and Relapse (B) samples, showing key genes found within the filtering criteria only. The x-axis for all plots is the variant allele frequency (VAF). A Gaussian kernel density estimator is used to estimate the mutational density (weighted by copy number) of the mutations plotted in the upper subfigures. Lower subfigures (scatter plots) display each mutation found. The y-axis of each lower subfigure is the depth of coverage. Each mutation in the scatter plot are given a glyph that indicates the level of multi-omic data available for the given mutation. See legend for glyph assignments.