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Figure 1 | BMC Bioinformatics

Figure 1

From: A computational method for drug repositioning using publicly available gene expression data

Figure 1

HyperLinks in Network II of Breast Cancer on adding Drug Nodes associated with Letrozole and 5aDHT. The red color node is the disease node representing Breast Cancer and the purple nodes represent the drug nodes, namely 5aDHT and Letrozole. The green colored nodes are the gene nodes representing the genes associated with Breast Cancer. All gene nodes are connected to the disease node. The gene nodes are also connected to the drug nodes that make them oppositely regulated. The hyperlinks are observed where both disease-gene (blue) and drug-gene (magenta) edges are incident on a single gene node (green). All the gene nodes that are connected to both the disease node and the drug node Letrozole form one hyperedge. Similarly another hyperedge associated with the drug node 5aDHT can also be observed.

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