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Table 2 The 14 physicochemical properties identified by SVM-BAC.

From: Characterizing informative sequence descriptors and predicting binding affinities of heterodimeric protein complexes

Rank Aaindex_ID Description MED
1 GUYH850105 Apparent partition energies calculated from Chothia index [19] 35.18
2 SNEP660104 Principal component IV [20] 32.71
3 RACS820113 Value of theta (i) (Rackovsky-Scheraga, 1982) [40] 31.48
4 MITS020101 Amphiphilicity index (Mitaku et al., 2002) [41] 31.48
5 MAXF760103 Normalized frequency of zeta R (Maxfield-Scheraga, 1976) [42] 27.77
6 CIDH920104 Normalized hydrophobicity scales for alpha/beta-proteins (Cid et al., 1992) [43] 19.13
7 AURR980119 Normalized positional residue frequency at helix termini C"' (Aurora-Rose, 1998) [44] 17.90
8 TANS770103 Normalized frequency of extended structure (Tanaka-Scheraga, 1977) [45] 16.66
9 CHOP780101 Normalized frequency of beta turn (Chou-Fasman,1978a) [21] 12.96
10 PALJ810107 Normalized frequency of alpha-helix in all-alpha class (Palau et al., 1981) [28] 12.96
11 QIAN880116 Weights for beta-sheet at the window position of -4 (Qian-Sejnowski, 1988) [46] 12.96
12 PALJ810110 Normalized frequency of beta-sheet in all-beta class (Palau et al., 1981) [28] 10.49
13 TAKK010101 Side-chain contribution to protein stability (kJ/mol) (Takano-Yutani, 2001) [47] 9.25
14 Nm-Protein Average medium-range contacts folding [17] 4.32