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Table 2 Summary of network properties for disease genes and drug target genes in the human interactome

From: A comparative study of disease genes and drug targets in the human protein interactome

Disease category No. of proteins Degree Betweenness (1.0 × 104) Clustering coefficient
  Disease Target Disease Target Disease Target Disease Target
Cancer 270 171 24.59 48.34 2.78 6.40 0.14 0.13
Cardiovascular 145 273 19.43 25.41 2.04 3.56 0.13 0.11
Immune 264 70 20.47 32.41 2.19 5.69 0.16 0.14
Metabolic 487 187 21.13 18.56 2.51 2.91 0.15 0.08
Nervous 125 249 16.68 23.25 1.81 2.73 0.17 0.11
Total 1065 643 20.25 26.12 2.23 3.51 0.15 0.12