A comparative study of disease genes and drug targets in the human protein interactome

BMC Bioinformatics

Table 2 Summary of network properties for disease genes and drug target genes in the human interactome

Disease category	No. of proteins		Degree		Betweenness (1.0 × 10⁴)		Clustering coefficient
	Disease	Target	Disease	Target	Disease	Target	Disease	Target
Cancer	270	171	24.59	48.34	2.78	6.40	0.14	0.13
Cardiovascular	145	273	19.43	25.41	2.04	3.56	0.13	0.11
Immune	264	70	20.47	32.41	2.19	5.69	0.16	0.14
Metabolic	487	187	21.13	18.56	2.51	2.91	0.15	0.08
Nervous	125	249	16.68	23.25	1.81	2.73	0.17	0.11
Total	1065	643	20.25	26.12	2.23	3.51	0.15	0.12

ISSN: 1471-2105