Figure 2
From: Identifying overlapping mutated driver pathways by constructing gene networks in cancer
The relationship between the genes in each module from the GBM dataset. (Left) Nodes represent genes in seven modules found by NBM from GBM dataset. Genes with "(A)" appended are amplification mutations, genes with "(D)" appended are deletion mutations, and genes with no annotation are SNVs. Edges connect genes which appear in the same gene set. Color of nodes indicates membership in different signaling pathways as important for GBM: p53, RB and RTK/RAS/PI(3)K signaling pathways. (Right) Known interactions between genes in each driver pathway: inhibit, activate and interact. And p-value of each driver pathway is given from DAVID functional annotation tool whose website is http://david.abcc.ncifcrf.gov/summary.jsp.